

Get Clear, Concise Answers to Your Top Questions About Platelet-Rich Plasma (PRP) Injections for Rotator Cuff Tear
Platelet-Rich Plasma (PRP) is a treatment that uses your own blood to promote healing. Platelets are cells in your blood that help with clotting and contain special proteins called growth factors, which are crucial for tissue repair. To make PRP, a doctor draws a small amount of your blood and spins it in a centrifuge. This separates and concentrates the platelets and plasma from the rest of the blood cells. The resulting concentrated plasma, rich in platelets, is then injected directly into the injured area.
When injected into a damaged rotator cuff tendon, the high concentration of growth factors in PRP helps stimulate and speed up your body's natural healing process. It works by attracting repair cells to the site of the tear, improving blood supply to the tendon, and reducing long-term inflammation. This can help repair partial tears, strengthen the tendon, and relieve pain.
PRP is typically recommended for patients who have:
A PRP injection cannot fully repair or reattach a complete, full-thickness tear where the tendon has entirely detached from the bone. Full-thickness tears usually require surgery to physically reattach the tendon. However, in some cases, PRP might be used alongside surgery to improve tissue healing, or it may be used to manage pain and improve function in patients who cannot undergo surgery.
The procedure is simple and done in an outpatient setting, taking about 30 to 45 minutes:
You will feel a pinch when the blood is drawn and when the local numbing medicine is injected into your shoulder skin. During the PRP injection itself, you may feel pressure or a temporary increase in soreness in the joint. A local anesthetic is used on the skin and surrounding tissues to minimize discomfort, but it is not injected directly into the tendon with the PRP because anesthetics can sometimes interfere with the platelets' effectiveness.
Because PRP is made from your own blood, the risk of an allergic reaction or disease transmission is virtually zero. However, as with any injection, there are minor risks, which include:
PRP relies on your body's natural inflammatory response to kickstart the healing process. Anti-inflammatory medications (like ibuprofen, naproxen, aspirin, and Celebrex) block inflammation, which can stop the PRP from working effectively. You should stop taking these medications for at least 7 to 10 days before the injection and for about 4 to 6 weeks after, as advised by your healthcare team. Tylenol (acetaminophen) is generally safe to use for pain relief instead.
To prepare for the procedure:
Immediately after your injection, you should:
You should rest the shoulder from structured exercise for the first week. After about 7 to 14 days, you can usually start a gentle, supervised physical therapy program focusing on range of motion. Passive stretching is followed by progressive strengthening as the tendon heals. Heavy lifting and sports should be avoided for at least 4 to 6 weeks, or until your doctor clears you.
PRP is not an instant pain reliever. Because it relies on tissue regeneration, most patients begin to notice improvement in pain and mobility after 4 to 6 weeks, with continued healing over several months. While many patients get significant relief from a single injection, a series of 2 to 3 injections spaced a few weeks apart may be recommended depending on the size and severity of the tear.
While both treatments aim to reduce pain, they work very differently:
In most regions, PRP injections are considered elective or experimental, and they are typically not covered by standard provincial health insurance plans (like OHIP) or most private insurance policies. Patients usually pay out-of-pocket for the procedure. It is best to check directly with your private insurance provider to see if they offer any coverage or health spending accounts that can be used.
Clinical studies show that PRP injections have a success rate of about 70% to 80% for patients with partial-thickness rotator cuff tears and tendinopathy. Success is measured by a significant reduction in pain and a noticeable improvement in shoulder function and strength. Results are best when the injection is combined with a dedicated physical therapy program.
We encourage you to write down any specific questions you have and discuss them thoroughly with your surgeon, doctor, or physical therapist. They are your best resource for personalized advice and care.
Disclaimer: This brochure provides general information and is not a substitute for professional medical advice. Always consult your doctor or qualified healthcare provider with any questions you may have regarding your specific medical condition and treatment plan.
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