

Get Clear, Concise Answers to Your Top Questions About Platelet-Rich Plasma (PRP) Injections for Shoulder Osteoarthritis
PRP therapy is a non-surgical treatment that uses a concentrated mixture of your own blood to promote healing. Platelets are cells in your blood that help with clotting and contain natural proteins called growth factors, which are essential for repairing tissues. By concentrating these platelets and injecting them into a damaged area, like an arthritic shoulder joint, PRP aims to stimulate the body's natural healing processes and reduce inflammation.
Shoulder osteoarthritis occurs when the protective cartilage covering the ends of your shoulder bones wears down over time. While PRP cannot rebuild lost cartilage, the concentrated growth factors in the injection can help reduce joint inflammation, decrease pain, and improve the lubrication within the joint. This helps the shoulder move more smoothly and can slow down the further degeneration of joint tissues.
You may be a good candidate for PRP if you have mild-to-moderate shoulder osteoarthritis and have not found sufficient relief from conservative treatments such as physical therapy, activity modification, or over-the-counter pain medications. It is often preferred by patients looking for non-surgical options that utilize their body's own healing mechanisms. PRP may be less effective for advanced, severe 'bone-on-bone' osteoarthritis.
The preparation process is straightforward and takes place right in the clinic:
The entire preparation process takes about 15 to 20 minutes.
The procedure is performed in an outpatient clinic setting and involves the following steps:
The injection itself takes only a few minutes, and a small bandage is placed over the injection site.
You will feel a pinch when the needle is inserted, and you may experience a feeling of pressure or mild discomfort as the PRP is injected into the joint. To minimize discomfort, a local anesthetic (numbing medicine) is often applied to the skin at the injection site. Some temporary soreness or aching in the shoulder is common for a few days after the procedure as the healing process begins.
PRP offers several unique advantages when compared to traditional treatments:
Unlike steroid injections which can work within days, PRP works by stimulating natural tissue healing and reducing inflammation over time. Most patients begin to feel improvement in their pain and shoulder mobility within 2 to 4 weeks after the injection. The benefits typically continue to build over the next few months as healing progresses.
The number of injections depends on the severity of your osteoarthritis and your response to the treatment. Many patients experience significant relief from a single PRP injection. However, a series of 2 to 3 injections spaced several weeks apart is sometimes recommended to achieve the best results. Your healthcare team will customize a plan based on your progress.
Immediately after the procedure, you should plan to rest your shoulder:
Because PRP is made from your own blood, the risks are extremely low. However, as with any injection, there are minimal risks which include:
These side effects are typically mild and resolve within a few days.
You will need to temporarily modify your activities to give the PRP the best environment to work:
Yes, physical therapy is highly recommended. Once the initial post-injection soreness resolves, a structured physical therapy program helps maximize the benefits of PRP. Physical therapy will focus on:
This combined approach offers the best long-term outcomes.
Currently, most private insurance companies and government health plans (such as Medicare or provincial health plans) do not cover PRP injections, as they are often categorized as investigational or regenerative treatments. You should contact your insurance provider directly to verify coverage. Payment plans or out-of-pocket costs can be discussed with the clinic.
Clinical studies show that PRP injections can significantly reduce pain and improve shoulder function for up to 6 to 12 months, and sometimes longer, in patients with mild-to-moderate osteoarthritis. While PRP is not a cure for osteoarthritis and cannot reverse joint damage, it is a highly effective tool for managing symptoms, improving quality of life, and delaying the need for more invasive surgical procedures.
We encourage you to write down any specific questions you have and discuss them thoroughly with your surgeon, doctor, or physical therapist. They are your best resource for personalized advice and care.
Disclaimer: This brochure provides general information and is not a substitute for professional medical advice. Always consult your doctor or qualified healthcare provider with any questions you may have regarding your specific medical condition and treatment plan.
Curated educational materials to help you make informed decisions about your orthopaedic bone & joint conditions.


